Flu-Hospitalizations, Group G Strep Outbreak, and more

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Invasive Group G Strep in Long Term Care Facilities

September 11, 2025

In this Issue

Flu-associated hospitalizations, 2024-25 season	Invasive Group G strep outbreak, long term care facility — PA

WEEKLY REPORT

Influenza-Associated Hospitalizations During a High Severity Season

The U.S. 2024-25 flu season had the highest recorded flu hospitalization rate since 2010-11, although proportions of patients admitted to an intensive care unit and who required invasive mechanical ventilation were similar to past seasons. Only about one-third of hospitalized patients were vaccinated.

• Notes from the Field: Invasive Group G β-Hemolytic Streptococcus Outbreak at a Long-Term Care Facility

  β-hemolytic group G Streptococcus (GGS) is a normal commensal organism but is increasingly recognized as a cause of invasive disease secondary to soft tissue infections, including cellulitis. In November 2024, the Pennsylvania Department of Health was notified of two GGS–positive blood cultures from residents of the same long-term care facility who were receiving wound care. Both patients were hospitalized for sepsis and cellulitis; one of the two died. Two other residents had positive wound cultures and were treated with antibiotics. Genomic analysis suggested isolates were highly related. Multiple infection control breaches were identified.

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MOST READ THIS WEEK

• Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2025–26 Influenza Season 
• Highly Pathogenic Avian Influenza A(H5N1) Virus Infection in a Child with No Known Exposure — San Francisco, California, December 2024–January 2025 
• Suicide Rates by Industry and Occupation — National Vital Statistics System, United States, 2021 
• Outbreak of Neisseria meningitidis Conjunctivitis in Military Trainees — Texas, February–May 2025 
• CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022 

In Case You Missed It

Human Metapneumovirus Seasonality and Co-Circulation with Respiratory Syncytial Virus — United States, 2014–2024

Circulation of both hMPV and RSV declined significantly during the 2020–21 respiratory virus season when the COVID-19 pandemic began. During the 2022–23 and 2023–24 seasons, RSV season offsets have been occurring earlier than usual in late winter, and typical hMPV circulation patterns have returned, with peak circulation in spring.

Notes from the Field: Primary Amebic Meningoencephalitis Associated with Nasal Irrigation Using Water from a Recreational Vehicle — Texas, 2024

A fatal case of PAM occurred in an otherwise healthy adult woman who used tap water obtained from her recreational vehicle (RV) in a nasal irrigation device. Although N. fowleri was not isolated from the RV water supply, the water was found to be inadequately disinfected.

U.S. Centers for Disease Control and Prevention

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