New in MMWR: Mpox on Cruise Ships, JYNNEOS Vaccine Recommendations, and more

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June 18, 2025

In this Issue

WEEKLY REPORT

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Clade II Mpox Infections Among Cruise Ship Passengers and Crew Members

In 2024, CDC was notified of eight mpox cases on four cruise ships: four among crew members and four among passengers. All cases occurred among men who had sex with men; five of eight patients had not been vaccinated against mpox.

  • Clade Ib Mpox Outbreak

    48 clade Ib mpox cases were diagnosed in Kenya July 2024–February 2025, many among people who worked along a highway linking Kenya to other East and Central African countries with ongoing clade Ib mpox outbreaks, including truck drivers and sex workers.

  • Use of JYNNEOS (Smallpox and Mpox Vaccine, Live, Nonreplicating) for Persons Aged ≥18 Years at Risk for Mpox During an Mpox Outbreak: Recommendations of the Advisory Committee on Immunization Practices

    In 2023, the Advisory Committee on Immunization Practices (ACIP) recommended the 2-dose JYNNEOS vaccine series for people 18 and older at risk for mpox during any mpox outbreak. ACIP also voted to recommend the vaccine series for people 18 and older at risk for acquiring mpox during the ongoing U.S. clade IIb outbreak that began in 2022, including but not limited to men who have sex with men who, during the past 6 months, have had or anticipate experiencing a new diagnosis of one or more sexually transmitted infections, more than one sex partner, sex at a commercial sex venue, or sex in association with a large public event in a geographic area where mpox transmission is occurring.

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MOST READ THIS WEEK

CONTINUING EDUCATION

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New MMWR and Medscape CE on Changes in Health Indicators Among Caregivers

In Case You Missed It

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Tick-Borne Encephalitis Vaccine: Recommendations of the Advisory Committee on Immunization Practices, United States, 2023

Tick-borne encephalitis (TBE) infection is a risk for certain travelers and any laboratory workers who work with the virus. In 2021, a TBE vaccine was licensed for the first time in the United States. CDC’s Advisory Committee on Immunization Practices (ACIP) has issued new recommendations for use of the vaccine.

CDC Guidelines for the Prevention and Treatment of Anthrax, 2023

To help protect the public’s health, CDC has published updated recommendations for the prevention and treatment of anthrax, including best practices for the clinical management of anthrax, including anthrax meningitis.

U.S. Centers for Disease Control and Prevention

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